Variable Selection in Untargeted Metabolomics and the Danger of Sparsity

Objective

To study the metabolic effects of treatment with NR in a cohort of patients with ataxia-telangiectasia (AT).

Study Design

Comparative study in 14 patients with AT

Dose

25 mg/kg

Duration

4 months

Key Outcomes

  • NR-related pathways and metabolites significantly increased after NR supplementation.

Published Study
Clinical, Ataxia Telangiectasia, Neurological HealthANAD Staff